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Previous Versions

Previous Versions

Space Ranger 4.0.1 (Jun 12, 2025)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 885 MB
    md5sum: b0beb100947717cee8c7ad0d7a9f0247
    curl -o spaceranger-4.0.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-4.0.1.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=oLNBVbhfZgsEBemmklkj2R7qSMuHLu9FHLvTSoP9o~Y-KT72COepMRMrHz0GacnQd9P2kXZuWYK0MUJjscN09xHaM4H57VvFCYRFgvygSoXXHRiO3DQMRXD0eJapWca1Fi20x9V6H92rhj06YWvk2HCxdnGwReX7rPJG6Esrd8d1QDrtVbJJoIAq9CZyycnkCTRRDIcnHfd3GfM4MtPUI7zM-SFyyjVvL5mQL-tpDWfkEufhLM2sw0L~EdSjne354G5UL4zy280OdIyC9gwFonNL1W45AqlX4TVC8A0S02X4JEZ~1lYsF3GeLJtw5l097HF~D9Z2dIpQ49K-Frs9Lg__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 582 MB
    md5sum: 3610ff948a6f8129cf49509f1bb34970
    curl -o spaceranger-4.0.1.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-4.0.1.tar.xz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=hD-DLtOjYbP~AJ2wDWf1axYhPuLkK6hLqNINyvDyBePg5A21wEfJHhpfcRrOTUXoj7FLZYfgfsBsUX358DIsXs5tGKha9TP8ILl8ykFv2xDp6DuqyG~3hWR4OnqYhBbMDOB-72f8nfZ3trsIi3i5fKyz-m-nH0tRU6bT3J7LYtVc0lVOnjGANSWs7j1-6~uwhnmzlKMQnloq7-vTxYE2sA0QdEC8IDXP4nf4hxyHqvXXZ-En-3tlxZ09yZSVQ-zsodn6W3eA-p0Y7xSkFWTCutlbcrZAdLeKWH6Fhng9p2KVddJ~kHL6Rd1Aa-FCBlZ5N2cWFJBVvWHfd1f1YiiijQ__"

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Space Ranger v4.0.1 highlights

  • Space Ranger v4.0 now supports Visium HD 3' Gene Expression!
  • Cell and nucleus segmentation are now included for Visium HD and Visium HD 3' data with H&E images.
  • Space Ranger v4.0 now features a new UMI-based registration algorithm for Visium HD and Visium HD 3' data.
  • Starting with v4.0, anonymized telemetry data is collected and sent to 10x Genomics.
Release notes

Space Ranger 3.1.3 (Feb 6, 2025)

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    Download for Linux 64-bit (tar.gz)
    File size: 829 MB
    md5sum: 2cc7128cd538108d2a8a737ec54df484
    curl -o spaceranger-3.1.3.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.3.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=BRzOLjMcwcyeanEuuuENTpi9ZNEcB2p2EaDPC6xkXpLV2YLyspXq7z7A7cyZ1k2PmP0iDLBKNGqSNpMd8pwHCBOePfBTOUWWl~Nr1CECzGq4U7rNgLSkGj3kABAOddfXjdamhE1osGp7OrHhGoR9Rz8kokcf8DjW-TM6RRKbiys9KUrv0~HENm0VUMYkuAY6deOKoziv37yyRqWOFfLorlCEkbYXqzqy3Wk4BwTfsf1QTud0R~FdHSvBm1ogLTLa2xVaYMjZccpBFxyspcfnu6r3e2-xTudbei2Myrs-cGeEp6hdydvJ5hOltLyVWm2IQ2vZKdniJ7wrphN~mdFnfA__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 529 MB
    md5sum: 2756aa7e3b66139059667117546c41bb
    curl -o spaceranger-3.1.3.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.3.tar.xz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=fwgeFaiQ1F4tE2Scb92Fbdfo25yIWUOUOi2IdN2BeLfkwnX28g2xAjmJb3Bi9W4LdTvnQ~WdKyWCMBwxIrZKAhXXZIF3uZO2UE70hnGW8jKh4MNW-QEasWOFUdKeIYl9lYwLXBRgCMh2exXcM3R~yszlykFNoCb2z~iU~94QLoJ6Ai75rkgU~us9oMW10efVVvq5fVYBJt8N9EXkKr2WlPJw7aBgtDkkU7jX4NCOLEq2lvHXP12efUoy7lMIguQvQAsHSqApOXTdWXHwxYWAOS9Q3u4f-IKyg1jjyGC-q5s2epN4eoCQUk7j2OrDyekNZbKVWvmh33E8of-41CFlPQ__"

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Space Ranger v3.1.3 highlights

  • Restored support for AVX1 machines.
  • Other miscellaneous bug fixes.

Space Ranger 3.1.2 (Nov 18, 2024)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 867 MB
    md5sum: 949088b1e2cc5bd03079b60a65b41d39
    curl -o spaceranger-3.1.2.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.2.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=D4ZaG6RJt1RiC1Osf~-hf3EhEAOYTZYFgvinE9VkccVwZRhziGXqYuY~wfWIuBwNZvkDOzzpAUnZ~dc9zixVhJod0efmS1oaHck~AOtqPxq6ewtkuhmwurX-48~gEuR72TzGKkyATjOFwQq~zNH4fBtv1bpBVWwpWj4QcMyIdjBbORip3nK3KfC2LuTT6y34nSNQB6fT-Vda-H0VtLmDsQ6quIy8Wiahmr9S7yYlwdTpLsldPuT4Ore651MlrPoWad-AORgRO6gD~LI348-fVK-Su0hDxvzD6AKmJaemAYVXXadHsVUdZduJlkZV8l1il9uILjrnvy7jp-IqXG0aKg__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 552 MB
    md5sum: 5a923ae250eea2974fd1cef7b2f9c1e2
    curl -o spaceranger-3.1.2.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.2.tar.xz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=Cx9CWEqIIhgm9HtyWRw1O9j6MwDqGogcSdnWC0-SGVKCzv8dt3I7YeIEfFxVxY5TeRN3Pas0FN~gtugEh2~vUcj9WWK5r2M6VOzoHC9jdI3NIo9CSK3pOoBjkDDDtGVKUM2zN4hKeWpyW1OcBFQ9iScNDzakCkSZn4QqIAgZr57NrVAnBpu4yiVKCW9WFMGgbX3IzKi5EQYigEjU-LaGnWypM3Jc0kgmalg2NTpvu7YcbEUbo02guGKmBG-v2ZYuluoiWNP7CiXtHfhnIhC6hMzU-EX9TIjiR9skHxOD8kumhQAeeup76YnT502vUYiJdE3hDeZyr4b4s3ZJ7blzpg__"

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Space Ranger v3.1.2 highlights

  • In Space Ranger v3.1.2, the pipeline automatically corrects Visium HD CytAssist images generated with instrument firmware v2.1 to account for a bug that affects registration between gene expression data and the microscope image.
  • Adds metrics “Number of UMIs per mm squared of Tissue” and “Number of Reads per mm squared of Tissue” to the web_summary.html file.

Space Ranger 3.1.0 (Aug 28, 2024)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 827 MB
    md5sum: 13a2c82adfb1f1efb737e2be121000d1
    curl -o spaceranger-3.1.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.0.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=kD5kC6UZZKxXllQhFg8Obfwju9IPyyDQFbYtUIie8xx5sEy3fFkLaS18EM8MAksCuEIOHWStJrjCgAQA28M888RFe1lHOWJaoPpz3o70lLDI1Pl77ePhmu-csXCbmkd~u6kaO6ZFCZpmHN5fmJZCnomb-O1jbsx1n5Vo4ef9z12aVTR-REBLDtqiyWz6Vmexo90j3B8ZEppYDqqvhOWnI8yWQ4mn3i8NB-BIXrQ8NBWZ4gM9AnUsV2jJbdcbJII1L9fb4F4juD97dSvCcQB-0UhQ9kXMOwqqdhQhZyBLghHVSG0tLcR23crFhKdL-VkTzvXZdUV9OwbIn6gGCBy1YQ__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 527 MB
    md5sum: 28010d3724e9effc488470a961fe39fd
    curl -o spaceranger-3.1.0.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.1.0.tar.xz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=K1UyiGfwEllpVu4beOYSlhQxlYrVlImPuKRc~MfcGyuZfsMgsbnfMpwoq2nbFj4ha0spNFrdLqi-aTWKACeWTQxr67LVgGY0LWKxm4FaSzY85qarf1Gxlm9MycxCML1PFzpJW5pdfZUQnsoKVJR0-PZzF~r810wrs1bt-6g30ZvPPdtupH~fwFRrlexe3PKB-CyHnbxBGd4OZSY7HO4k9UM2G7hkS3EBUS1EmOM4t0SpE5NJy7QCCUt1-xXXhDy2T2xpfKh32AqCOoIQUy~9Pk5ldytvSQf6JkMkoZg-Ba-XQyQA1eKbmEShKcvDu5GcxgObg-xHAVrexcFarLjtNA__"

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Space Ranger 3.1.0 highlights

  • In Space Ranger v3.1.0, the pipeline has been overhauled to significantly improve the CytAssist to microscope image registration process.

Space Ranger 3.0.1 (May 31, 2024)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 757 MB
    md5sum: ae65e7ffdddbb966277b7d1776f8c63c
    curl -o spaceranger-3.0.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.0.1.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=i~Kx-F~bBVgNxEpFurlOlUYt5~4C5~GG8WantmWL2teoJtnekDSvgZtRzjPrKADHs5AbDdrIXHJ-8HpYBFGBvifewZrab2w6deUUv6R5CCrURDfL0gomrxfIXGeC2MfKiRTzQw4fdgqjPpBQ5MVzNDVp7bo8iUkdo9tgNm~5TL8iqmjC22bbN-cePv1cp6bhyo42SmEExM5Pv93140cqxdXNkYDx3Tb5Ysdn088N0E~AedQDL0-qQzwQDnbEWAdONi5SMZo2U-0o9jWmCMS6O-GlqWIJgGPQ-5XsYIcTd7r5B6QiyYBfMbgtGxe~Juzlc-7VwDWs5QrMnXe163zqWw__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 481 MB
    md5sum: 451495ee2074ff9adbac49ff8851ea1b
    curl -o spaceranger-3.0.1.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.0.1.tar.xz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=RDLljWF6v3IPKoWhrlFilaE3tRAZIgbCFP8xwuMZ3I2aBmjP-Vg8WlofJ~x35G6344yaSQqW543X2qe025rTu8hkPGjDRt6TSotWGnLUlIjPZjH2QoqpXCTSzVtsANC3PuUsn2gcwr3uvjLIo-9POt2PYCt~UMbyJJW6tE8ZLlKReZ4R739h20XMSp8FH1vrf1ZEMnzWxAX-DySbTD81dZnHWYxi2Gyn1mikYf9jhiz~8YSMCNHRTMItxA52FM3D-Drd~QHNwszKu0F8HCVROcjlPipLr8ah1pnrQaa24wJXqPx2aYC-~ewIMt01IUZIVdePQOjUSghCvdLmz1QS3w__"

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Space Ranger 3.0.1 highlights

  • Space Ranger v3.0 now supports Visium HD!
  • Space Ranger v3.0.1 includes bug fixes and other improvements.

Space Ranger 3.0.0 (Mar 25, 2024)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 795 MB
    md5sum: 19f4443f10cf94aff5768bd8968cb214
    curl -o spaceranger-3.0.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.0.0.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=FJl0OyyVVXsySps-jKeC7o~mTY2Hs8lmuTafm7c83NPaFVQGwvkupm7gLdE4oN58gUMYQKBK8x3I9xv0cdsZlWiGgQEx5AzV3Zi7Is9xRsiIYpQdNs8HiimEZr1z6E9AMTdN4BHZk~uouSR2nY7raDaVIGYCpTyP78WEN18j3c~s-pUJ~EQK~N1UH3RNLtMEKs2emcBCzGoqAv5HdeiRueMo9Hd14fjC8GvESHbDiNrZCDGKJUJ9Z1CqGxRiMqvik7z5o-9yJt5BdRk4HPuEYtMiWU5rgX1Ssp33fNVEjPp3ilLL2-ix1cbrbum23hRfMn80ZNKthztoZTps6wzwiA__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 507 MB
    md5sum: cd02b83fe849672066c40a1734819432
    curl -o spaceranger-3.0.0.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-3.0.0.tar.xz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=VWuvrNiuoEKsy39j2nCrxTwjW5usUDy~kCHs2VROGhLDuPpx-ZzKHPbra01o-S1PMr6FfsFtogLRYT-HfzmlFhvkcTkE-jYqaRX55~4ZAEs3BKyGXk9o5paeJa9AMa3-H~T89Bm4CykVp~JN3B621P7qO6blIWeJVyOQr1IxXCQ-ABqvlKuXHnuZHwoSJMot~pKp8~jkzmiD1h6BbW-P9xHZPcGE5DkU5CqFgQNeeodRCTe9SQuOvbuIMpMZ6DY2x3QDpLypL7F6ynkg0FgAUsMsWOUWSFuZdGAY4poHBbyuqqO~1jpJcxXAdwENvV3BRwR5zQwtndsm7S1yJ2xKhA__"

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Space Ranger 3.0.0 highlights

  • Space Ranger now supports Visium HD!

Space Ranger 2.1.1 (Oct 2, 2023)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 707 MB
    md5sum: 0ef64524af2735bd2a0fc9eef5a605f6
    curl -o spaceranger-2.1.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.1.1.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=An~2vsWPRbuXjF4mIpFreqV04-nfpglDLQGaN1tjLT3OgS8RABXUDdGujQsF21rC6434lwbj9BVM4UoTWcMqLsWPJAgwcOoptM5XyN2vIvCVHJ4kXZoIr0qXmFXxKyGoR32BVYC3EZYjAHXCyAuz93GQcWGASrszFmkba6JaYwHzPjxZeYcc9AIfbLwoIJrwEqIALJyT7yOQdVLY3wL99SQ75EPJgrYWokrJnH2X6AlmMfjLqygNM1xPnLl97KCaM27C212B0M~4sxPUPYUGp5e5yJhxbRHNsJQvbgsh7r8F7q9aYOJEnUWiXg2jArJtGqJdKqWPS7QFHbxSTi~eaw__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 465 MB
    md5sum: e1204bb11b3589bc5d5af244b51bfc18
    curl -o spaceranger-2.1.1.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.1.1.tar.xz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=OwHBFGHaAXId8qsTg-BKMnM9y5I846Hdy5Glq2l5pjW3pDddJ9oPHEWUKrXTU3Qu6Y2a~6Od-tsAjZICQBm0RyTdEgGM-tdqKOSyagE10Suk9y5xCqOKziuZ2j6O~ZYl80oa8eh7UNcjA7THmAgiIblfmGydrTSX9jnvihK43mJW8O303p09~F0DlAlhQqpWV3dMhmp0NuSWoA~~x508EvqhLP~ar9Zxo77UJYDJcpH9qfWeiYGAiy~yErLEmjBMsBNdku1apN45W76~8U914rqP4sQIdMJe1IfCIVZURCPgqzF0a917bjXLDO9cBpPL6ADkTs8kIT5H9sW9HycrfQ__"

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Space Ranger 2.1.1 highlights

  • Fixed a bug where 8-bit grayscale images were inadvertently turned into 8-bit RGB color images for tissue registration.

Space Ranger 2.1.0 (May 16, 2023)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 707 MB
    md5sum: ee94c453c44770b2b69d6be46b948e3e
    curl -o spaceranger-2.1.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.1.0.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=PcgzYqzieSp4JzsXjAUy~1~zOw5VA2gt07vsq7TYVS4x-Otwhy4af5mdXjIbZKm0f8b9HpB3DJ4Zye5dCPKttYbZomE~-QDJbbVP59Z8qCbRgSL84RW6Mh-9IYjTNx2m2nR-i117sMVh39FsYUEt99Uj19lvV-DEZduisoqmf7C7Vi8I1b5~Ywi~KQ~3BE2aHww0AzSyUM~uDcYHK8AZNrZF2nvO0hkO8wz7eT0rZTbFiYGGqZrHZlkiIGDFda8I3iJfS3YyELpYrEq9GY5X2NDfc2J1xEyDOF0RnwLqkQ5J2UvlLG5Bq1rXwdf701DRH~PRZx~QYMZn8FR8TJEzyQ__"
  • tar.xz compression

    Download for Linux 64-bit (tar.xz)
    File size: 465 MB
    md5sum: a0d90129a81c41cbdd728e23a4d25161
    curl -o spaceranger-2.1.0.tar.xz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.1.0.tar.xz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=O~EoQsOmP104B5Lfg~5hjazYz7O~MjO4fMBQzsy2xUM~KBXVxDN8jCTwCI6TLcnYKjVmLH8r2HL~ZfAuAX305f1zlcYBQQQblAjoy0W3CmwOY3VFCD7yu-hwJLGFAQQEgSaRzwA-ZDtiPK~NGVGoWqkVGC6-EdaPD~xNUaJqebe1foebRc98t0baAvdvuAFIH9xftcZoxKhH7AfUSVf1FqaEykEq1ETo2cI~O9BdZHYH9RvMFDOv8YhucVLm506H7VwOZzbKeCncaX49VOU9X6271rqZZzMlAbYCcsqI9trLH~vw-wdNbA~ALXf~v4G2dwxC7zxL0E8lJEf1uKOoow__"

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Space Ranger 2.1.0 highlights

  • New feature: Gene + Protein Expression on Visium CytAssist.
  • New feature: Reference-free spot deconvolution.
  • Added support for bigtiff (btf, tf2, and tf8) image file extensions.

Space Ranger 2.0.1 (Dec 7, 2022)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 664 MB
    md5sum: 26151804338ae4d4b44151232bd64b50
    curl -o spaceranger-2.0.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.0.1.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=ImTtENESR7ZjzPyMwefBFDjywYA-AR0KITbsle9lJmBzDQ4fMv-jLtEjEC5oe98897R7augSPJ~Z8X0jxen4c8UI3I7BoT1EBXtps1OSjeVPmr1JXvatOq71b994SfJExCKuSPrJzkReWg3rGsEEO51-oWsCrS7MAahI93xT8TtY4Zx5M3p3OSnz5ZPojkv5JnbqDNuUfVNp~QX5pJvEvLsSb9N5ju5a2ROCABSlLvpzcRWP3ilWHtXu1WlbuNFC7Ve825nYStA6oJ9Ua7dZ4C23~xxqrTwzG9KGg0ghE~Lu1Q3hpkSwPy3h7lEZhnVF2Ven3Uw~u1VVllxjXA0nCQ__"

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Space Ranger 2.0.1 highlights

  • Reclustering workflow now supports generating a UMAP projection in addition to the t-SNE projection.
  • Visium Image Manual Aligner now includes additional support for images with difficult to detect fiducials.
  • A new Spatial Enrichment table which allows users to sort and filter features by their Moran’s I value for Visium Spatial Gene Expression is added.

Space Ranger 2.0.0 (Jul 18, 2022)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 662 MB
    md5sum: aec9ec128c7bc9fbf9fd6d31aa390d4c
    curl -o spaceranger-2.0.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-2.0.0.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=dTtpmcFACA-grJlT0~Ao4ddeuJk5nioJg5UWAY8m5VHhHC87q0CRCQUbJ9~TGcc3H6PTpmtc~Ci2doEGcT0vlF3tBlnATcyljmYIKPtW-ensKtuwAFXngpkjNZIrEzIbh7Iq-pKUpCv2EX8vZRhILOfjJjEGs0ZCZTFlUhFzMg9U~wHHI0EY~vZGWWZ-b5EGZNXXsn2YxNxPeO4wv4IzwW4WHVQ0QohlPDAtyPpaPHlKfRZWGrHArvlZ4116z5nFeFykdf0qMCDmvZ3J2KbVu2rnm1FBrm7TauDWgSZdbZzWywUn6KMjH8Itj~7x76ieyDJffQmwWtLS~fhgJaHYDw__"

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Space Ranger 2.0.0 highlights

  • Space Ranger now supports CytAssist-enabled Gene Expression analysis and includes image registration between the CytAssist image and the microscope image of the same tissue section.
  • spaceranger count now quantifies fluorescence intensity in the image at every barcoded-spot location.

Space Ranger 1.3.1 (Nov 1, 2021)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: c2eb73125d9ee731fa825ea3734be1b4
    curl -o spaceranger-1.3.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.3.1.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=Aa0pJ9yTR8PWZB8BpNp23hWpWAgYku3jfXeZn4FSa4nJt4umnpfFqtuNJDQR2hJ-~BBbkyNW1vsHDxbXYKiiIyahgS6kPHqma~lEsOAm1aelkWIOmuveTMqV1Ukp4hZAjfSEy84FqOIS034OoqobcBfmqU1uBhBvVwNTU50~ksfjibM8TAk5Z70-gqfcN3S0lRAnGwiqz6kEI6vbG7EgKHL1iw1f5W6iSxL4D6T3QemVJcA4a14yXroN2MT4ORr8NRT0iP-TpKshTGqUfw9eEFJ2dQHe8cPsh6-iyCyoWJnKgltN0POndiNjtCcr9GpgOM5BNQwpVDZRMH4Ir8XqJQ__"

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Space Ranger 1.3.1 highlights

  • Adds an alert if image alignment would have produced a different result if the --reorient-images option was specified.
  • Update warning for low fraction of reads confidently mapped to the probe set to be more informative.
  • Unsets additional sysconfig environment variables prior to pipeline execution, which may otherwise interfere with the pipeline conda environment.
  • Fixes an issue with mkfastq when bcl2fastq requires LD_LIBRARY_PATH.

Space Ranger 1.3.0 (Jun 9, 2021)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: ede7f98db5adf7785e35ae0508c48f74
    curl -o spaceranger-1.3.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.3.0.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=MR89Ekqm91g-bVEY6aQHKhubdBWwzR5qQ7Kl2ajdut9eMPS7OZmL-VksEiNT-XjMnP5C8Q3GGs3IRNra3nqSq2hQSWp-sJx6tC-gyDoVkntRm3N60iyXzzWTZMVcIFM2ouup09IiR8PnHe7hhWgb-qmnIEHehiwoQM~yX8gOM2EDk0RF3OS4bw2Bu~Fph~BaqX1E6g5NQF-OV~LUYlOUq3On7xgT7nFIpnzD39qSwbAS-hhBRjbyKxBSftL49xjXU7wGkKiBeA2HcffTihLDoYAzuEwhIUbtx~CcPzP1abrQoE3yO8NfAFdUPCETU~RF6pPIaVFxThWLqp3nRXTlrw__"

Download is unavailable on mobile devices.

Space Ranger 1.3.0 highlights

  • The recommended operating systems for Space Ranger 1.3.0 are CentOS 7 or Ubuntu 14 Linux variants or newer. CentOS 6 and Ubuntu 12 are still supported but have been deprecated.
  • Gene Expression analysis from formalin fixed paraffin embedded (FFPE) samples is now available in Space Ranger and is invoked by specifying the --probe-set option when running the spaceranger count command. Space Ranger 1.3.0 or later is required to analyze FFPE data.
  • Space Ranger now calculates the Moran's I spatial autocorrelation metric on a per-gene basis.

Space Ranger 1.2.2 (Feb 3, 2021)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: 3280a085714ce7c894dc14b76312bcda
    curl -o spaceranger-1.2.2.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.2.2.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=fb-YuLPQRnDDFydvBo0rZBb5LXGQox9h8v0bIpWCEXl67HpAhVHQ2tAi3lLAAh-MrSglSVnX~5soGsxGf95va~jPR9Xv9ZM4LIjDMbsn1sHGC-HlV3QfuCvgs1h-ed4gtl1HhltAyqw775yZiw1yHR7iUBuYZ7CzRyixko4YU5d~p8UeJRcI7iwQ3ZzsVzJmeDVsYtlKLZyiSCghp9mt~pw8HxKxKrDzduQtwUFH5P~ucckn6JOgZI11y0rrjQtehTbU4~4qmIuomSxa-7J4q8yPtE5hNlXspkLpTFfIYXz7xP9c6WAvTCI86Vm2KPjZJoQSG8PHxWf7VhMPc65BBg__"

Download is unavailable on mobile devices.

Space Ranger 1.2.2 highlights

  • Adds support for pyramid TIFFs, or TIFFs with multiple pages of the same image at different resolutions.
  • Fixes an issue where targeted samples run against new references would fail preflight.

Space Ranger 1.2.1 (Dec 10, 2020)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: c24ecfc95c5e4f1c268354c5934da98e
    curl -o spaceranger-1.2.1.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.2.1.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=bg0dxp8quYenMPR5UeZDjDT-QIPd4nldL8Dw9ZogGhm4J6eyDqwwQLRo-CjEFWc3T3CYLy1vvsBOcI-nAi0HbxvRzm9rzJA-c4hJI45NVCXJkFqXFoHTsVIEe2repoOk-e~k9IdjqBsqfMeRy5Ri9qakkDWNPtBxOpNKg-e8PMcmJX7dEbzatd0ahhiySuxeJEG4r4ZBCf5SFPIFYDBa72JiZ-1SGx2CiBWuHOffEWjOnIcxZfqXqW3rPhY34Pq~bkaGGacbmOFHpK7nqdaKGwgZsaNQNr73AjVJMh4Emmr1t1JdbnLyLCkWfWo8oWKQjN-dsHU6JH02ljM1alObGQ__"

Download is unavailable on mobile devices.

Space Ranger 1.2.1 highlights

  • Fixed an issue in aggr where files would fail to be copied on NFSv4 File Systems.
  • Disables multithreading in mkref to address an issue where mkref would fail on hardware without AVX support.
  • Better error handling if the pipeline fails due to a missing .env.json file due to an incomplete copy of the application folder.

Space Ranger 1.2.0 (Oct 27, 2020)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: fc21902700779111afc3c813bbb0ff5e
    curl -o spaceranger-1.2.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.2.0.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=D56TXTocF9~FrsslYh-70SqgnzaPQOrOG9UftWj-dLhRyrbGnQe17cfa9wxdI6wuQafi8KTNq7PxY9W4hjMcKp2YbYQK~eFxCQCflFQy3E8V9DeC2mlBw5IihxjBG5hj5UbSx4ZVwuUXGnuMtyaZiM-nSzh8OICkqnIr9rg0P6284sF-bl8FMzIoYBI~QLVUZ62o4mL9XhFYzxbaVVjxQYyLnNuJpcYoou7JSH2OSNz-y30akdqkcyZbb49JhUiCLTcB2vuHHxtbVbaUf7UehTmW4hvuWss6JvodjyVyIy2mhWghve~BcnGIe2dOoCy7RYV-AYkfFlRivWhViiwRfQ__"

Download is unavailable on mobile devices.

Space Ranger 1.2.0 highlights

  • Targeted Gene Expression analysis is available in Space Ranger 1.2.
  • Introduces the new spaceranger targeted-compare pipeline for direct comparative analysis of matched parent Whole Transcriptome Amplification (WTA) and Targeted Gene Expression datasets.
  • Includes the spaceranger targeted-depth subcommand to estimate sequencing depths appropriate for Spatial Targeted Gene Expression experiments.
  • A new command line option, --no-bam, instructs the pipeline not to construct BAM files.

Space Ranger 1.1.0 (Jun 23, 2020)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.2 GB
    md5sum: 708b93997295db31bc457b3d9af79ca2
    curl -o spaceranger-1.1.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.1.0.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=jajgSc1H3OGo27HIKAw0x8TXa4RGWGty0L1Om9G78UxFLqnJbAjyBvvT9edDRJ1yxgZ9kcNiCYkZCnen674wLhyFDU7JelGWnE1sJ-wjv~N8XmGwNECwMoJ2yxJkex2fBoucpfpoyN~~2h7Yq2mTYNETpVtMtl4uaEjrD26QqqqphAig725cKURWhGbsbseokfw2PJsdcQ1Sv6jNA8QzM-dCMJ~DRied2RQB3Q1HiFs2CBLQxHS1cNXXIoTPrFySfIwps3RtzxZUFlyP6PYTNYV0Z-QZl5eZDEPt13Y35HFBB08h6zdmzMcwG9Ny-a25oAHKeYnTFG3n7N3-DQbuow__"

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Space Ranger 1.1.0 highlights

  • Support for fluorescence imaging input such as IHC/IF.
  • Aggregation of multiple datasets.
  • Optional automatic rotation of slide images.

Space Ranger 1.0.0 (Dec 2, 2019)

  • tar.gz compression

    Download for Linux 64-bit (tar.gz)
    File size: 1.3 GB
    md5sum: 5cc7fb86d0cbff7df687b11575efb7cb
    curl -o spaceranger-1.0.0.tar.gz "https://cf.10xgenomics.com/releases/spatial-exp/spaceranger-1.0.0.tar.gz?Expires=1774625981&Key-Pair-Id=APKAI7S6A5RYOXBWRPDA&Signature=NKf0ohPNeHZ0~uGm2PunCYDLJlhHgGg1FaaJQ2Wxj5uDKDDtb0eJJkaD-MjMfxVbvRuzt5hbkOUt3CAr5qsWZJUAIB-CtP5l6NzMhS~Pl1UdrQuONtykdh-xSe2Jw5OEuB2AZYsVgTjsMLMiri~-BiWWyd2CMWaRgqxNKdP035oFNyv3O-ouQQ9Xp~310C6AYu9aFSLbzHOvsi1iuvpPVcGSUFdLoTVv~P119LQQJnZY2XWDS2YuFNvDF~MZICywusOI3~8h2f7fqeJUAZtk0gw49qqeZqIa4MCu0yRjMu761NZC2QNDKJDQQF7R4dDvgbe4K~ShS6-94mFi5p7eLA__"

Download is unavailable on mobile devices.

Space Ranger 1.0.0 highlights

  • Initial release of Space Ranger.